Mapping Brain Variability in Human Populations. Just as faces differ among different individuals, brain structure varies even among normal individuals, and even more so in disease. This map displays the magnitude and principal directions of anatomical variability in the brain, based on a group of 40 normal subjects scanned with MRI. Pink colors indicate brain regions with large anatomical variability across subjects, blue colors low variability. The ellipsoidal glyphs are elongated along directions in which variation is greatest. The nested, transparent glyphs represent the probabilities of different anatomical variations, and are used to detect abnormal anatomical differences in Alzheimer's Disease. These maps help distinguish pathological changes from normal variations. 
image by Paul Thompson, Andrew Lee, Kiralee Hayashi, Agatha Lee, and Arthur Toga


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